Research Scientist – Bioinformatics Analyst

Job Summary:

We have an exciting opportunity to join our team as a Bioinformatics Programmer.

The Center for Cancer and Blood Disorders (CCBD) at the University of Colorado/Anschutz Medical Campus is seeking a highly motivated, enthusiastic individual to manage and analyze data generated by Next-Generation DNA sequencers in conjunction with the experiments performed by our faculty. This is a great opportunity to quickly acquire new skills, develop and publish new tools and methods, analyze challenging datasets and be a co-author on multiple published studies.

Key Responsibilities:

· Work with emerging approaches for analyzing multi-omics data analysis and integration (15%)

· Perform robust data quality control and validation (15%)

· Analyze various types of sequencing data analysis (e.g. single cell sequencing, RNA-seq, ChIP-seq, ATAC-seq, Hi-C-seq, bisulfite sequencing, whole-genome sequencing) (15%)

· Work closely with bench scientists to understand and help accomplish their research goals (12%)

· Integrate different types of genomics data and prepare concise presentations of computational results (12%)

· Design, implement, execute standard pipelines for routine genomics data analyses, and customized pipelines for collaborative research projects (11%)

· Perform robust data quality control and validation (10%)

· Perform other duties (such as meta-analyses of existing GEO deposited and other data sets) as assigned by faculty collaborators (10%)

Work Location:

Hybrid – this role is eligible for a hybrid schedule of 3 days per week on campus and as needed for in-person meetings.

Why Join Us:

The Hematology/Oncology/Bone Marrow Transplant Section within the Pediatrics Department is nationally recognized for providing excellent consultation, clinical care, and surgery for children and adolescents with cancer and blood disorders. Faculty in the Section study childhood bleeding disorders, brain and blood tumors, bone marrow failure and sickle cell disease. Our renowned team of multidisciplinary experts provides thousands of children who are fighting cancer and blood disorders with world-class care and cutting-edge treatments – all while pioneering new therapies and cures through groundbreaking research.

Why work for the University?

We have AMAZING benefits and offer exceptional amounts of holiday, vacation and sick leave! The University of Colorado offers an excellent benefits package including:

• Medical: Multiple plan options
• Dental: Multiple plan options
• Additional Insurance: Disability, Life, Vision
• Retirement 401(a) Plan: Employer contributes 10% of your gross pay
• Paid Time Off: Accruals over the year (based on percentage of time)
• Vacation Days: 22/year (maximum accrual 352 hours)
• Sick Days: 15/year (unlimited maximum accrual)
• Holiday Days: 11/year
• Tuition Benefit: Employees have access to this benefit on all CU campuses
• ECO Pass: Reduced rate RTD Bus and light rail service

There are many additional perks & programs with the CU Advantage.

Qualifications:

Minimum Qualifications:

Applicants must meet minimum qualifications at the time of hire.

· Graduation from an accredited university with a Masters in Computational Biology, System Biology, Computer Science or related field

· Minimum of 3 years of programming language experience with Python, R, Java, Go, Bash, SQL, MySQL

· Minimum of 3 years of tools and library experience with Git, Linux, Scikit-Learn, Numpy, Pandas, Samtools, Bedtools, Bowtie2, STAR, Nextflow, Snakemake

Condition of Employment:

· Must be willing and able to pass a national criminal background check

Preferred Qualifications:

· Graduation from an accredited university with a PhD in Computational Biology, System Biology, Computer Science or related field

· Prior experience with brain cancer disease models

· Experience with stem cell biology and relevant assays (flow cytometric analysis and flow sorting of stem or progenitor population

· Prior experience in chromatin biology

Knowledge, Skills and Abilities:

· Ability to function autonomously but exercise sound judgment in seeking appropriate supervision

· Skilled in communicating effectively and facilitating group processes

· Ability to establish and maintain effective working relationships with researchers, and other team members

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